Publications

Rahman Z, Khuroo T, Mohamed EM, Dharani S, Kayalar C, Kuttolamadom MA, Sangaré LO, Khan MA. Pyrimethamine 3D printlets for pediatric toxoplasmosis: design, pharmacokinetics, and anti-toxoplasma activity Expert Opin Drug Deliv. 2023 Feb;20(2):301-311. doi: 10.1080/17425247.2023.2169272. Epub 2023 Jan 29. PMID: 36639201
Krishnamurthy S, Maru P, Wang Y, Bitew MA, Mukhopadhyay D, Yamaryo-Botté Y, Paredes-Santos TC, Sangaré LO, Swale C, Botté CY, Saeij JPJ. CRISPR Screens Identify Toxoplasma Genes That Determine Parasite Fitness in Interferon Gamma- Stimulated Human Cells mBio. 2023 Apr 25;14(2):e0006023. doi: 10.1128/mbio.00060-23. Epub 2023 Mar 14. PMID: 36916910

Sangaré LO, Wang Y, Arranz-Solís D, Saeij JPJ. CRISPR screen to determine the in vivo fitness of Toxoplasma genes. STAR Protoc. 2021 May 3;2(2):100520. doi: 10.1016/j.xpro.2021.100520. eCollection 2021 Jun 18. PMID: 34013213

Wang Y, Sangaré LO, Paredes-Santos TC, Saeij JPJ. Toxoplasma Mechanisms for Delivery of Proteins and Uptake of Nutrients Across the Host-Pathogen Interface. Annu Rev Microbiol. 2020 Sep 8;74:567-586. doi: 10.1146/annurev-micro-011720-122318. Epub 2020 Jul 17.PMID: 32680452
Mukhopadhyay D, Sangaré LO, Braun L, Hakimi MA, Saeij JP. Toxoplasma GRA15 limits parasite growth in IFN-y activated fibroblasts through TRAF ubiquitin ligases EMBO J. 2020 May 18;39(10):e103758. doi: 10.15252/embj.2019103758. Epub 2020 Apr 15.PMID: 32293748
Wang Y, Sangaré LO, Paredes-Santos TC, Hassan MA, Krishnamurthy S, Furuta AM, Markus BM, Lourido S, Saeij JPJ. Genome-wide screens identify Toxoplasma gondii determinants of parasite fitness in IFN-y activated murine macrophages. Nat Commun. 2020 Oct 16;11(1):5258. doi: 10.1038/s41467-020-18991-8. PMID: 33067458

Sangaré LO, Yang N, Konstantinou EK, Lu D, Mukhopadhyay D, Young LH, Saeij JPJ. Toxoplasma GRA15 Activates the NF-kB Pathway through Interactions with TNF Receptor-Associated Factors mBio. 2019 Jul 16;10(4):e00808-19. doi: 10.1128/mBio.00808-19. PMID: 31311877
Sangaré LO, Ólafsson EB, Wang Y, Yang N, Julien L, Camejo A, Pesavento P, Sidik SM, Lourido S, Barragan A, Saeij JPJ. In Vivo CRISPR Screen Identifies TgWIP as a Toxoplasma Modulator of Dendritic Cell Migration Cell Host Microbe. 2019 Oct 9;26(4):478-492.e8. doi: 10.1016/j.chom.2019.09.008.PMID: 31600500
Wang Y, Cirelli KM, Barros PDC, Sangaré LO, Butty V, Hassan MA, Pesavento P, Mete A, Saeij JPJ. Three Toxoplasma gondii Dense Granule Proteins Are Required for Induction of Lewis Rat Macrophage Pyroptosis PMID: 30622189 Sangaré LO, Alayi TD,

Westermann B, Hovasse A, Sindikubwabo F, Callebaut I, Werkmeister E, Lafont F, Slomianny C, Hakimi MA, Van Dorsselaer A, Schaeffer-Reiss C, Tomavo S. Unconventional endosome-like compartment and retromer complex in Toxoplasma gondii govern parasite integrity and host infection Nat Commun. 2016 Apr 11;7:11191. doi: 10.1038/ncomms11191.PMID: 27064065

2015

Sloves PJ, Mouveaux T, Ait-Yahia S, Vorng H, Everaere L, Sangare LO, Tsicopoulos A, Tomavo S. Apical Organelle Secretion by Toxoplasma Controls Innate and Adaptive Immunity and Mediates Long-Term Protection J Infect Dis. 2015 Nov 1;212(9):1449-58. doi: 10.1093/infdis/jiv250. Epub 2015 Apr 24.PMID: 25910629